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Mapping DNA cleavage by the Type ISP restriction-modification enzymes following long-range communication between DNA sites in different orientations

The prokaryotic Type ISP restriction-modification enzymes are single-chain proteins comprising an Mrr-family nuclease, a superfamily 2 helicase-like ATPase, a coupler domain, a methyltransferase, and a DNA-recognition domain. Upon recognising an unmodified DNA target site, the helicase-like domain h...

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Detalles Bibliográficos
Autores principales: van Aelst, Kara, Saikrishnan, Kayarat, Szczelkun, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666363/
https://www.ncbi.nlm.nih.gov/pubmed/26507855
http://dx.doi.org/10.1093/nar/gkv1129