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Computational learning on specificity-determining residue-nucleotide interactions

The protein–DNA interactions between transcription factors and transcription factor binding sites are essential activities in gene regulation. To decipher the binding codes, it is a long-standing challenge to understand the binding mechanism across different transcription factor DNA binding families...

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Detalles Bibliográficos
Autores principales: Wong, Ka-Chun, Li, Yue, Peng, Chengbin, Moses, Alan M., Zhang, Zhaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666365/
https://www.ncbi.nlm.nih.gov/pubmed/26527718
http://dx.doi.org/10.1093/nar/gkv1134