Cargando…

The current state of eukaryotic DNA base damage and repair

DNA damage is a natural hazard of life. The most common DNA lesions are base, sugar, and single-strand break damage resulting from oxidation, alkylation, deamination, and spontaneous hydrolysis. If left unrepaired, such lesions can become fixed in the genome as permanent mutations. Thus, evolution h...

Descripción completa

Detalles Bibliográficos
Autores principales: Bauer, Nicholas C., Corbett, Anita H., Doetsch, Paul W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666366/
https://www.ncbi.nlm.nih.gov/pubmed/26519467
http://dx.doi.org/10.1093/nar/gkv1136