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An endogenous protein inhibitor, YjhX (TopAI), for topoisomerase I from Escherichia coli

Almost all free-living bacteria contain toxin-antitoxin (TA) systems on their genomes and the targets of toxins are highly diverse. Here, we found a novel, previously unidentified TA system in Escherichia coli named yjhX-yjhQ. Induction of YjhX (85 amino acid residues) causes cell-growth arrest resu...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Yoshihiro, Inouye, Masayori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666372/
https://www.ncbi.nlm.nih.gov/pubmed/26553797
http://dx.doi.org/10.1093/nar/gkv1197