Characterisation of aptamer–target interactions by branched selection and high-throughput sequencing of SELEX pools

Nucleic acid aptamer selection by systematic evolution of ligands by exponential enrichment (SELEX) has shown great promise for use in the development of research tools, therapeutics and diagnostics. Typically, aptamers are identified from libraries containing up to 10(16) different RNA or DNA seque...

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Detalles Bibliográficos
Autores principales: Dupont, Daniel M., Larsen, Niels, Jensen, Jan. K., Andreasen, Peter A., Kjems, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666376/
https://www.ncbi.nlm.nih.gov/pubmed/26163061
http://dx.doi.org/10.1093/nar/gkv700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666376/
https://www.ncbi.nlm.nih.gov/pubmed/26163061
http://dx.doi.org/10.1093/nar/gkv700

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