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Detection of differentially methylated regions from whole-genome bisulfite sequencing data without replicates

DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Recent developments in whole genome bisulfite sequencing (WGBS) technology have enabled genome-wide measurements of DNA methylation at single base pair resolution. Many experiments have been c...

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Detalles Bibliográficos
Autores principales: Wu, Hao, Xu, Tianlei, Feng, Hao, Chen, Li, Li, Ben, Yao, Bing, Qin, Zhaohui, Jin, Peng, Conneely, Karen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666378/
https://www.ncbi.nlm.nih.gov/pubmed/26184873
http://dx.doi.org/10.1093/nar/gkv715