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Detection of differentially methylated regions from whole-genome bisulfite sequencing data without replicates
DNA methylation is an important epigenetic modification involved in many biological processes and diseases. Recent developments in whole genome bisulfite sequencing (WGBS) technology have enabled genome-wide measurements of DNA methylation at single base pair resolution. Many experiments have been c...
Autores principales: | Wu, Hao, Xu, Tianlei, Feng, Hao, Chen, Li, Li, Ben, Yao, Bing, Qin, Zhaohui, Jin, Peng, Conneely, Karen N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666378/ https://www.ncbi.nlm.nih.gov/pubmed/26184873 http://dx.doi.org/10.1093/nar/gkv715 |
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