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Dual-colour imaging of RNAs using quencher- and fluorophore-binding aptamers

In order to gain deeper insight into the functions and dynamics of RNA in cells, the development of methods for imaging multiple RNAs simultaneously is of paramount importance. Here, we describe a modular approach to image RNA in living cells using an RNA aptamer that binds to dinitroaniline, an eff...

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Detalles Bibliográficos
Autores principales: Arora, Ankita, Sunbul, Murat, Jäschke, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666381/
https://www.ncbi.nlm.nih.gov/pubmed/26175046
http://dx.doi.org/10.1093/nar/gkv718