Sumoylation of Sir2 differentially regulates transcriptional silencing in yeast

Silent information regulator 2 (Sir2), the founding member of the conserved sirtuin family of NAD(+)-dependent histone deacetylase, regulates several physiological processes including genome stability, gene silencing, metabolism and life span in yeast. Within the nucleus, Sir2 is associated with tel...

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Detalles Bibliográficos
Autores principales: Hannan, Abdul, Abraham, Neethu Maria, Goyal, Siddharth, Jamir, Imlitoshi, Priyakumar, U. Deva, Mishra, Krishnaveni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666389/
https://www.ncbi.nlm.nih.gov/pubmed/26319015
http://dx.doi.org/10.1093/nar/gkv842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666389/
https://www.ncbi.nlm.nih.gov/pubmed/26319015
http://dx.doi.org/10.1093/nar/gkv842

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