Direct-Coupling Analysis of nucleotide coevolution facilitates RNA secondary and tertiary structure prediction

Despite the biological importance of non-coding RNA, their structural characterization remains challenging. Making use of the rapidly growing sequence databases, we analyze nucleotide coevolution across homologous sequences via Direct-Coupling Analysis to detect nucleotide-nucleotide contacts. For a...

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Detalles Bibliográficos
Autores principales: De Leonardis, Eleonora, Lutz, Benjamin, Ratz, Sebastian, Cocco, Simona, Monasson, Rémi, Schug, Alexander, Weigt, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666395/
https://www.ncbi.nlm.nih.gov/pubmed/26420827
http://dx.doi.org/10.1093/nar/gkv932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666395/
https://www.ncbi.nlm.nih.gov/pubmed/26420827
http://dx.doi.org/10.1093/nar/gkv932

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