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SerRS-tRNA(Sec) complex structures reveal mechanism of the first step in selenocysteine biosynthesis

Selenocysteine (Sec) is found in the catalytic centers of many selenoproteins and plays important roles in living organisms. Malfunctions of selenoproteins lead to various human disorders including cancer. Known as the 21st amino acid, the biosynthesis of Sec involves unusual pathways consisting of...

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Detalles Bibliográficos
Autores principales: Wang, Caiyan, Guo, Yu, Tian, Qingnan, Jia, Qian, Gao, Yuanzhu, Zhang, Qinfen, Zhou, Chun, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666401/
https://www.ncbi.nlm.nih.gov/pubmed/26433229
http://dx.doi.org/10.1093/nar/gkv996