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SerRS-tRNA(Sec) complex structures reveal mechanism of the first step in selenocysteine biosynthesis
Selenocysteine (Sec) is found in the catalytic centers of many selenoproteins and plays important roles in living organisms. Malfunctions of selenoproteins lead to various human disorders including cancer. Known as the 21st amino acid, the biosynthesis of Sec involves unusual pathways consisting of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666401/ https://www.ncbi.nlm.nih.gov/pubmed/26433229 http://dx.doi.org/10.1093/nar/gkv996 |