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Nuclear Magnetic Resonance-Assisted Prediction of Secondary Structure for RNA: Incorporation of Direction-Dependent Chemical Shift Constraints

[Image: see text] Knowledge of RNA structure is necessary to determine structure–function relationships and to facilitate design of potential therapeutics. RNA secondary structure prediction can be improved by applying constraints from nuclear magnetic resonance (NMR) experiments to a dynamic progra...

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Detalles Bibliográficos
Autores principales: Chen, Jonathan L., Bellaousov, Stanislav, Tubbs, Jason D., Kennedy, Scott D., Lopez, Michael J., Mathews, David H., Turner, Douglas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666457/
https://www.ncbi.nlm.nih.gov/pubmed/26451676
http://dx.doi.org/10.1021/acs.biochem.5b00833