Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis

OBJECTIVE: Human Hepatocellular Carcinoma (HCC) is the fifth most frequent neoplasm worldwide and the most serious complication of long-standing chronic liver diseases (CLD). Its development is associated with chronic inflammation and sustained oxidative stress. Deregulation of apurinic apyrimidinic...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Maso, Vittorio, Mediavilla, María Gabriela, Vascotto, Carlo, Lupo, Francesco, Baccarani, Umberto, Avellini, Claudio, Tell, Gianluca, Tiribelli, Claudio, Crocè, Lory Saveria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666459/
https://www.ncbi.nlm.nih.gov/pubmed/26624999
http://dx.doi.org/10.1371/journal.pone.0143289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666459/
https://www.ncbi.nlm.nih.gov/pubmed/26624999
http://dx.doi.org/10.1371/journal.pone.0143289

Ejemplares similares