BRAFV600E-Associated Gene Expression Profile: Early Changes in the Transcriptome, Based on a Transgenic Mouse Model of Papillary Thyroid Carcinoma

BACKGROUND: The molecular mechanisms driving the papillary thyroid carcinoma (PTC) are still poorly understood. The most frequent genetic alteration in PTC is the BRAFV600E mutation–its impact may extend even beyond PTC genomic profile and influence the tumor characteristics and even clinical behavi...

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Detalles Bibliográficos
Autores principales: Rusinek, Dagmara, Swierniak, Michal, Chmielik, Ewa, Kowal, Monika, Kowalska, Malgorzata, Cyplinska, Renata, Czarniecka, Agnieszka, Piglowski, Wojciech, Korfanty, Joanna, Chekan, Mykola, Krajewska, Jolanta, Szpak-Ulczok, Sylwia, Jarzab, Michal, Widlak, Wieslawa, Jarzab, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666467/
https://www.ncbi.nlm.nih.gov/pubmed/26625260
http://dx.doi.org/10.1371/journal.pone.0143688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666467/
https://www.ncbi.nlm.nih.gov/pubmed/26625260
http://dx.doi.org/10.1371/journal.pone.0143688

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