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E2-2 Dependent Plasmacytoid Dendritic Cells Control Autoimmune Diabetes

Autoimmune diabetes is a consequence of immune-cell infiltration and destruction of pancreatic β-cells in the islets of Langerhans. We analyzed the cellular composition of the insulitic lesions in the autoimmune-prone non-obese diabetic (NOD) mouse and observed a peak in recruitment of plasmacytoid...

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Detalles Bibliográficos
Autores principales: Hansen, Lisbeth, Schmidt-Christensen, Anja, Gupta, Shashank, Fransén-Pettersson, Nina, Hannibal, Tine D., Reizis, Boris, Santamaria, Pere, Holmberg, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666626/
https://www.ncbi.nlm.nih.gov/pubmed/26624013
http://dx.doi.org/10.1371/journal.pone.0144090