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Loss of Gadkin Affects Dendritic Cell Migration In Vitro

Migration is crucial for the function of dendritic cells (DCs), which act as outposts of the immune system. Upon detection of pathogens, skin- and mucosa-resident DCs migrate to secondary lymphoid organs where they activate T cells. DC motility relies critically on the actin cytoskeleton, which is r...

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Detalles Bibliográficos
Autores principales: Schachtner, Hannah, Weimershaus, Mirjana, Stache, Vanessa, Plewa, Natalia, Legler, Daniel F., Höpken, Uta E., Maritzen, Tanja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666629/
https://www.ncbi.nlm.nih.gov/pubmed/26624014
http://dx.doi.org/10.1371/journal.pone.0143883