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Fn14, a Downstream Target of the TGF-β Signaling Pathway, Regulates Fibroblast Activation
Fibrosis, the hallmark of human injuries and diseases such as serious burns, is characterized by excessive collagen synthesis and myofibroblast accumulation. Transforming growth factor-β (TGF-β), a potent inducer of collagen synthesis, has been implicated in fibrosis in animals. In addition to TGF-β...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666639/ https://www.ncbi.nlm.nih.gov/pubmed/26625141 http://dx.doi.org/10.1371/journal.pone.0143802 |