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Can Genetic Analysis of Putative Blood Alzheimer’s Disease Biomarkers Lead to Identification of Susceptibility Loci?

Although 24 Alzheimer’s disease (AD) risk loci have been reliably identified, a large portion of the predicted heritability for AD remains unexplained. It is expected that additional loci of small effect will be identified with an increased sample size. However, the cost of a significant increase in...

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Detalles Bibliográficos
Autores principales: Barber, Robert C., Phillips, Nicole R., Tilson, Jeffrey L., Huebinger, Ryan M., Shewale, Shantanu J., Koenig, Jessica L., Mitchel, Jeffrey S., O’Bryant, Sid E., Waring, Stephen C., Diaz-Arrastia, Ramon, Chasse, Scott, Wilhelmsen, Kirk C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666664/
https://www.ncbi.nlm.nih.gov/pubmed/26625115
http://dx.doi.org/10.1371/journal.pone.0142360