Large-scale identification of sequence variants impacting human transcription factor occupancy in vivo

The function of human regulatory regions depends exquisitely on their local genomic environment and cellular context, complicating experimental analysis of the expanding pool of common disease- and trait-associated variants that localize within regulatory DNA. We leverage allelically resolved genomi...

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Detalles Bibliográficos
Autores principales: Maurano, Matthew T., Haugen, Eric, Sandstrom, Richard, Vierstra, Jeff, Shafer, Anthony, Kaul, Rajinder, Stamatoyannopoulos, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666772/
https://www.ncbi.nlm.nih.gov/pubmed/26502339
http://dx.doi.org/10.1038/ng.3432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666772/
https://www.ncbi.nlm.nih.gov/pubmed/26502339
http://dx.doi.org/10.1038/ng.3432

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