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Large-scale identification of sequence variants impacting human transcription factor occupancy in vivo
The function of human regulatory regions depends exquisitely on their local genomic environment and cellular context, complicating experimental analysis of the expanding pool of common disease- and trait-associated variants that localize within regulatory DNA. We leverage allelically resolved genomi...
Autores principales: | Maurano, Matthew T., Haugen, Eric, Sandstrom, Richard, Vierstra, Jeff, Shafer, Anthony, Kaul, Rajinder, Stamatoyannopoulos, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666772/ https://www.ncbi.nlm.nih.gov/pubmed/26502339 http://dx.doi.org/10.1038/ng.3432 |
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