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A Survey of DICER1 Hotspot Mutations in Ovarian and Testicular Sex Cord-Stromal Tumors

Sertoli-Leydig cell tumors are characterized by the presence of somatic DICER1 hotspot mutations. In this study, we sought to define the association between DICER1 hotspot mutations and different morphologic subtypes of ovarian Sertoli-Leydig cell tumors. Furthermore, we aimed to assess whether DICE...

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Detalles Bibliográficos
Autores principales: Conlon, Niamh, Schultheis, Anne M, Piscuoglio, Salvatore, Silva, Annacarolina, Guerra, Esther, Tornos, Carmen, Reuter, Victor E, Soslow, Robert A, Young, Robert H, Oliva, Esther, Weigelt, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666775/
https://www.ncbi.nlm.nih.gov/pubmed/26428316
http://dx.doi.org/10.1038/modpathol.2015.115