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Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer

Acquired therapeutic resistance is the major drawback to effective systemic therapies for cancers. Aggressive triple-negative breast cancers (TNBC) develop resistance to chemotherapies rapidly, whereas the underlying mechanisms are not completely understood. Here we show that genotoxic treatments si...

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Detalles Bibliográficos
Autores principales: Niu, Jixiao, Xue, Aimin, Chi, Yayun, Xue, Jingyan, Wang, Wei, Zhao, Ziqin, Fan, Meiyun, Yang, Chuan He, Shao, Zhi-ming, Pfeffer, Lawrence M., Wu, Jiong, Wu, Zhao-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666837/
https://www.ncbi.nlm.nih.gov/pubmed/26028030
http://dx.doi.org/10.1038/onc.2015.189