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Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer
Acquired therapeutic resistance is the major drawback to effective systemic therapies for cancers. Aggressive triple-negative breast cancers (TNBC) develop resistance to chemotherapies rapidly, whereas the underlying mechanisms are not completely understood. Here we show that genotoxic treatments si...
Autores principales: | Niu, Jixiao, Xue, Aimin, Chi, Yayun, Xue, Jingyan, Wang, Wei, Zhao, Ziqin, Fan, Meiyun, Yang, Chuan He, Shao, Zhi-ming, Pfeffer, Lawrence M., Wu, Jiong, Wu, Zhao-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666837/ https://www.ncbi.nlm.nih.gov/pubmed/26028030 http://dx.doi.org/10.1038/onc.2015.189 |
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