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The Matricellular Protein CCN1 Suppresses Hepatocarcinogenesis by Inhibiting Compensatory Proliferation

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, and is on the rise in the United States. Previous studies showed that the matricellular protein CCN1 (CYR61) is induced during hepatic injuries and functions to restrict and resolve liver fibrosis. Here we...

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Detalles Bibliográficos
Autores principales: Chen, Chih-Chiun, Kim, Ki-Hyun, Lau, Lester F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666840/
https://www.ncbi.nlm.nih.gov/pubmed/26028023
http://dx.doi.org/10.1038/onc.2015.190