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A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity

The molecular mechanisms underlying spontaneous neoplastic transformation in cultured mammalian cells remain poorly understood, confounding recognition of parallels with the biology of naturally occurring cancer. The broad use of tumorigenic canine cell lines as research tools, coupled with the accu...

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Detalles Bibliográficos
Autores principales: Omeir, R., Thomas, R., Teferedegne, B., Williams, C., Foseh, G., Macauley, J., Brinster, L., Beren, J., Peden, K., Breen, M., Lewis, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666904/
https://www.ncbi.nlm.nih.gov/pubmed/25957863
http://dx.doi.org/10.1007/s10577-015-9474-8