Mycobacterium tuberculosis Infection Induces HDAC1-Mediated Suppression of IL-12B Gene Expression in Macrophages

Downregulation of host gene expression is one of the many strategies employed by intracellular pathogens such as Mycobacterium tuberculosis (MTB) to survive inside the macrophages and cause disease. The underlying molecular mechanism behind the downregulation of host defense gene expression is large...

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Detalles Bibliográficos
Autores principales: Chandran, Aneesh, Antony, Cecil, Jose, Leny, Mundayoor, Sathish, Natarajan, Krishnamurthy, Kumar, R. Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667035/
https://www.ncbi.nlm.nih.gov/pubmed/26697414
http://dx.doi.org/10.3389/fcimb.2015.00090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667035/
https://www.ncbi.nlm.nih.gov/pubmed/26697414
http://dx.doi.org/10.3389/fcimb.2015.00090

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