Cargando…

Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis

Introduction: In liver fibrosis activation of hepatic stellate cells (HSC) comprises phenotypical change into profibrotic and myofibroplastic cells with increased contraction and secretion of extracellular matrix (ECM) proteins. The small GTPase RhoA orchestrates cytoskeleton formation, migration, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Görtzen, Jan, Schierwagen, Robert, Bierwolf, Jeanette, Klein, Sabine, Uschner, Frank E., van der Ven, Peter F., Fürst, Dieter O., Strassburg, Christian P., Laleman, Wim, Pollok, Jörg-Matthias, Trebicka, Jonel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667086/ https://www.ncbi.nlm.nih.gov/pubmed/26696895 http://dx.doi.org/10.3389/fphys.2015.00359

Ejemplares similares

Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension
por: Klein, Sabine, et al.
Publicado: (2016)

Statins activate the canonical hedgehog-signaling and aggravate non-cirrhotic portal hypertension, but inhibit the non-canonical hedgehog signaling and cirrhotic portal hypertension
por: Uschner, Frank E., et al.
Publicado: (2015)

High risk of misinterpreting liver and spleen stiffness using 2D shear-wave and transient elastography after a moderate or high calorie meal
por: Kjærgaard, Maria, et al.
Publicado: (2017)

Extracellular Matrix Remodeling in Chronic Liver Disease
por: Ortiz, Cristina, et al.
Publicado: (2021)

A New Treatment for Chronic Hepatitis B and D Offers Novel Insights Into Obesity and Hepatic Steatosis
por: Schierwagen, Robert, et al.
Publicado: (2020)

Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats
por: Klein, Sabine, et al.
Publicado: (2019)

Hemodynamic Effects of the Non-Peptidic Angiotensin-(1-7) Agonist AVE0991 in Liver Cirrhosis
por: Klein, Sabine, et al.
Publicado: (2015)

Role of portal venous platelet activation in patients with decompensated cirrhosis and TIPS
por: Queck, Alexander, et al.
Publicado: (2020)

β-Arrestin2 is increased in liver fibrosis in humans and rodents
por: Schierwagen, Robert, et al.
Publicado: (2020)

Role of circulating angiogenin levels in portal hypertension and TIPS
por: Queck, Alexander, et al.
Publicado: (2021)

Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosis
por: Schierwagen, Robert, et al.
Publicado: (2015)

Hepatic inflammasome activation as origin of Interleukin-1α and Interleukin-1β in liver cirrhosis
por: Praktiknjo, Michael, et al.
Publicado: (2021)

MicroRNA-155 is upregulated in ascites in patients with spontaneous bacterial peritonitis
por: Lutz, Philipp, et al.
Publicado: (2017)

Serum markers of the extracellular matrix remodeling reflect antifibrotic therapy in bile-duct ligated rats
por: Schierwagen, Robert, et al.
Publicado: (2013)

Managing portal hypertension in patients with liver cirrhosis
por: Sauerbruch, Tilman, et al.
Publicado: (2018)

FXR agonist obeticholic acid reduces hepatic inflammation and fibrosis in a rat model of toxic cirrhosis
por: Verbeke, Len, et al.
Publicado: (2016)

Systemic Inflammation and Acute-on-Chronic Liver Failure: Too Much, Not Enough
por: Laleman, Wim, et al.
Publicado: (2018)

Etiology and Complications of Portal Vein Thrombosis
por: Trebicka, Jonel, et al.
Publicado: (2014)

Activation of the Alternate Renin-Angiotensin System Correlates with the Clinical Status in Human Cirrhosis and Corrects Post Liver Transplantation
por: Casey, Stephen, et al.
Publicado: (2019)

Beta-blockers in patients with liver cirrhosis: Pragmatism or perfection?
por: Sauerbruch, Tilman, et al.
Publicado: (2023)

The Role of miRNA-34a as a Prognostic Biomarker for Cirrhotic Patients with Portal Hypertension Receiving TIPS
por: Jansen, Christian, et al.
Publicado: (2014)

Left Ventricular Longitudinal Contractility Predicts Acute‐on‐Chronic Liver Failure Development and Mortality After Transjugular Intrahepatic Portosystemic Shunt
por: Jansen, Christian, et al.
Publicado: (2019)

Dynamic human liver proteome atlas reveals functional insights into disease pathways
por: Niu, Lili, et al.
Publicado: (2022)

Acute decompensation boosts hepatic collagen type III deposition and deteriorates experimental and human cirrhosis
por: Praktiknjo, Michael, et al.
Publicado: (2018)

The multikinase inhibitor regorafenib decreases angiogenesis and improves portal hypertension
por: Uschner, Frank Erhard, et al.
Publicado: (2018)

Quantification of liver fibrosis: extracellular volume fraction using an MRI bolus-only technique in a rat animal model
por: Luetkens, Julian A., et al.
Publicado: (2019)

Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats
por: Cremonese, Carla, et al.
Publicado: (2020)

microRNA‐200a: A stage‐dependent biomarker and predictor of steatosis and liver cell injury in human immunodeficiency virus patients
por: Austermann, Christian, et al.
Publicado: (2017)

Evolution of nodule stiffness might predict response to local ablative therapy: A series of patients with hepatocellular carcinoma
por: Praktiknjo, Michael, et al.
Publicado: (2018)

Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
por: Tyc, Olaf, et al.
Publicado: (2020)

Baseline Presence of NAFLD Predicts Weight Loss after Gastric Bypass Surgery for Morbid Obesity
por: Rheinwalt, Karl Peter, et al.
Publicado: (2020)

The calcium-activated potassium channel KCa3.1 is an important modulator of hepatic injury
por: Sevelsted Møller, Linda, et al.
Publicado: (2016)

Systemic MCP-1 Levels Derive Mainly From Injured Liver and Are Associated With Complications in Cirrhosis
por: Queck, Alexander, et al.
Publicado: (2020)

TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor
por: Klein, Sabine, et al.
Publicado: (2019)

Trust is good, control is better: technical considerations in blood microbiome analysis
por: Schierwagen, Robert, et al.
Publicado: (2020)

Interplay of Matrix Stiffness and Protein Tethering in Stem Cell Differentiation
por: Wen, Jessica H., et al.
Publicado: (2014)

Compartmentalization of Immune Response and Microbial Translocation in Decompensated Cirrhosis
por: Alvarez-Silva, Camila, et al.
Publicado: (2019)

Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview
por: Torres, Sandra, et al.
Publicado: (2020)

The Role of Macrophage-Inducible C-Type Lectin in Different Stages of Chronic Liver Disease
por: Schierwagen, Robert, et al.
Publicado: (2020)

The Specific NLRP3 Antagonist IFM-514 Decreases Fibrosis and Inflammation in Experimental Murine Non-Alcoholic Steatohepatitis
por: Torres, Sandra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j6luksfol108jpj78sed2j8fav