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Modeling the Transitions between Collective and Solitary Migration Phenotypes in Cancer Metastasis

Cellular plasticity during cancer metastasis is a major clinical challenge. Two key cellular plasticity mechanisms —Epithelial-to-Mesenchymal Transition (EMT) and Mesenchymal-to-Amoeboid Transition (MAT) – have been carefully investigated individually, yet a comprehensive understanding of their inte...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Jolly, Mohit Kumar, Lu, Mingyang, Tsarfaty, Ilan, Ben-Jacob, Eshel, Onuchic, Jose’ N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667179/
https://www.ncbi.nlm.nih.gov/pubmed/26627083
http://dx.doi.org/10.1038/srep17379