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Quantifying the heritability of glioma using genome-wide complex trait analysis

Genome-wide association studies (GWAS) have successfully identified a number of common single-nucleotide polymorphisms (SNPs) influencing glioma risk. While these SNPs only explain a small proportion of the genetic risk it is unclear how much is left to be detected by other, yet to be identified, co...

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Detalles Bibliográficos
Autores principales: Kinnersley, Ben, Mitchell, Jonathan S., Gousias, Konstantinos, Schramm, Johannes, Idbaih, Ahmed, Labussière, Marianne, Marie, Yannick, Rahimian, Amithys, Wichmann, H.-Erich, Schreiber, Stefan, Hoang-Xuan, Khe, Delattre, Jean-Yves, Nöthen, Markus M., Mokhtari, Karima, Lathrop, Mark, Bondy, Melissa, Simon, Matthias, Sanson, Marc, Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667278/
https://www.ncbi.nlm.nih.gov/pubmed/26625949
http://dx.doi.org/10.1038/srep17267