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Crystal structure of FadD32, an enzyme essential for mycolic acid biosynthesis in mycobacteria

Fatty acid degradation protein D32 (FadD32), an enzyme required for mycolic acid biosynthesis and essential for mycobacterial growth, has recently been identified as a valid and promising target for anti-tuberculosis drug development. Here we report the crystal structures of Mycobacterium smegmatis...

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Detalles Bibliográficos
Autores principales: Li, Wenjuan, Gu, Shoujin, Fleming, Joy, Bi, Lijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667280/
https://www.ncbi.nlm.nih.gov/pubmed/26628098
http://dx.doi.org/10.1038/srep15493