Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility

Pseudomonas aeruginosa is an opportunistic human pathogen for which new antimicrobial drug options are urgently sought. P. aeruginosa disulfide-bond protein A1 (PaDsbA1) plays a pivotal role in catalyzing the oxidative folding of multiple virulence proteins and as such holds great promise as a drug...

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Detalles Bibliográficos
Autores principales: McMahon, Roisin M., Coinçon, Mathieu, Tay, Stephanie, Heras, Begoña, Morton, Craig J., Scanlon, Martin J., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667283/
https://www.ncbi.nlm.nih.gov/pubmed/26627647
http://dx.doi.org/10.1107/S1399004715018519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667283/
https://www.ncbi.nlm.nih.gov/pubmed/26627647
http://dx.doi.org/10.1107/S1399004715018519

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