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Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1

The functional assembly of the synaptic release machinery is well understood; however, how signalling factors modulate this process remains unknown. Recent studies suggest that Wnts play a role in presynaptic function. To examine the mechanisms involved, we investigated the interaction of release ma...

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Detalles Bibliográficos
Autores principales: Ciani, Lorenza, Marzo, Aude, Boyle, Kieran, Stamatakou, Eleanna, Lopes, Douglas M., Anane, Derek, McLeod, Faye, Rosso, Silvana B., Gibb, Alasdair, Salinas, Patricia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667432/
https://www.ncbi.nlm.nih.gov/pubmed/26400647
http://dx.doi.org/10.1038/ncomms9302