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Functional classification of memory CD8(+) T cells by CX(3)CR1 expression

Localization of memory CD8(+) T cells to lymphoid or peripheral tissues is believed to correlate with proliferative capacity or effector function. Here we demonstrate that the fractalkine-receptor/CX(3)CR1 distinguishes memory CD8(+) T cells with cytotoxic effector function from those with prolifera...

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Detalles Bibliográficos
Autores principales: Böttcher, Jan P., Beyer, Marc, Meissner, Felix, Abdullah, Zeinab, Sander, Jil, Höchst, Bastian, Eickhoff, Sarah, Rieckmann, Jan C., Russo, Caroline, Bauer, Tanja, Flecken, Tobias, Giesen, Dominik, Engel, Daniel, Jung, Steffen, Busch, Dirk H., Protzer, Ulrike, Thimme, Robert, Mann, Matthias, Kurts, Christian, Schultze, Joachim L., Kastenmüller, Wolfgang, Knolle, Percy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667439/
https://www.ncbi.nlm.nih.gov/pubmed/26404698
http://dx.doi.org/10.1038/ncomms9306