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Serum bilirubin concentration is modified by UGT1A1 Haplotypes and influences risk of Type-2 diabetes in the Norfolk Island genetic isolate

BACKGROUND: Located in the Pacific Ocean between Australia and New Zealand, the unique population isolate of Norfolk Island has been shown to exhibit increased prevalence of metabolic disorders (type-2 diabetes, cardiovascular disease) compared to mainland Australia. We investigated this well-establ...

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Detalles Bibliográficos
Autores principales: Benton, M. C., Lea, R. A., Macartney-Coxson, D., Bellis, C., Carless, M. A., Curran, J. E., Hanna, M., Eccles, D., Chambers, G. K., Blangero, J., Griffiths, L. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667444/
https://www.ncbi.nlm.nih.gov/pubmed/26628212
http://dx.doi.org/10.1186/s12863-015-0291-z