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Epigenetic inactivation of the extracellular matrix metallopeptidase ADAMTS19 gene and the metastatic spread in colorectal cancer

BACKGROUND: ADAMTS19 encodes a member of the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) protein family with emerging roles in carcinogenesis and metastasis. ADAMTS shares several distinct protein modules including a propeptide region, a metalloproteinase domain, a...

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Detalles Bibliográficos
Autores principales: Alonso, Sergio, González, Beatriz, Ruiz-Larroya, Tatiana, Durán Domínguez, Mercedes, Kato, Takaharu, Matsunaga, Akihiro, Suzuki, Koichi, Strongin, Alex Y., Gimènez-Bonafé, Pepita, Perucho, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667455/
https://www.ncbi.nlm.nih.gov/pubmed/26634009
http://dx.doi.org/10.1186/s13148-015-0158-1