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Large-scale production and antiviral efficacy of multi-target double-stranded RNA for the prevention of white spot syndrome virus (WSSV) in shrimp

BACKGROUND: RNA interference (RNAi) is a specific and effective approach for inhibiting viral replication by introducing double-stranded (ds)RNA targeting the viral gene. In this study, we employed a combinatorial approach to interfere multiple gene functions of white spot syndrome virus (WSSV), the...

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Detalles Bibliográficos
Autores principales: Thammasorn, Thitiporn, Sangsuriya, Pakkakul, Meemetta, Watcharachai, Senapin, Saengchan, Jitrakorn, Sarocha, Rattanarojpong, Triwit, Saksmerprome, Vanvimon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667486/
https://www.ncbi.nlm.nih.gov/pubmed/26626024
http://dx.doi.org/10.1186/s12896-015-0226-9