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Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes

INTRODUCTION: Mesenchymal stem/stromal cells (MSCs) improve the metabolic function of co-cultured hepatocytes. The present study aimed to further enhance the trophic effects of co-culture with hepatocytes using hypoxic preconditioning (HPc) of the MSCs and also to investigate the underlying molecula...

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Detalles Bibliográficos
Autores principales: Qin, Harry H., Filippi, Céline, Sun, Song, Lehec, Sharon, Dhawan, Anil, Hughes, Robin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667488/
https://www.ncbi.nlm.nih.gov/pubmed/26626568
http://dx.doi.org/10.1186/s13287-015-0218-7