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Hypoxic preconditioning potentiates the trophic effects of mesenchymal stem cells on co-cultured human primary hepatocytes
INTRODUCTION: Mesenchymal stem/stromal cells (MSCs) improve the metabolic function of co-cultured hepatocytes. The present study aimed to further enhance the trophic effects of co-culture with hepatocytes using hypoxic preconditioning (HPc) of the MSCs and also to investigate the underlying molecula...
Autores principales: | Qin, Harry H., Filippi, Céline, Sun, Song, Lehec, Sharon, Dhawan, Anil, Hughes, Robin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667488/ https://www.ncbi.nlm.nih.gov/pubmed/26626568 http://dx.doi.org/10.1186/s13287-015-0218-7 |
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