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Overexpression of α-synuclein in oligodendrocytes does not increase susceptibility to focal striatal excitotoxicity
BACKGROUND: Multiple system atrophy (MSA) is a fatal adult-onset neurodegenerative disease characterized by α-synuclein (α-syn) positive oligodendroglial cytoplasmic inclusions. The latter are associated with a neuronal multisystem neurodegeneration targeting central autonomic, olivopontocerebellar...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667489/ https://www.ncbi.nlm.nih.gov/pubmed/26627686 http://dx.doi.org/10.1186/s12868-015-0227-6 |