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Overexpression of α-synuclein in oligodendrocytes does not increase susceptibility to focal striatal excitotoxicity

BACKGROUND: Multiple system atrophy (MSA) is a fatal adult-onset neurodegenerative disease characterized by α-synuclein (α-syn) positive oligodendroglial cytoplasmic inclusions. The latter are associated with a neuronal multisystem neurodegeneration targeting central autonomic, olivopontocerebellar...

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Detalles Bibliográficos
Autores principales:	Kuzdas-Wood, Daniela, Fellner, Lisa, Premstaller, Melanie, Borm, Carlijn, Bloem, Bastiaan, Kirik, Deniz, Wenning, Gregor K., Stefanova, Nadia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667489/ https://www.ncbi.nlm.nih.gov/pubmed/26627686 http://dx.doi.org/10.1186/s12868-015-0227-6

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