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Fusion transcript loci share many genomic features with non-fusion loci

BACKGROUND: Fusion transcripts are found in many tissues and have the potential to create novel functional products. Here, we investigate the genomic sequences around fusion junctions to better understand the transcriptional mechanisms mediating fusion transcription/splicing. We analyzed data from p...

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Detalles Bibliográficos
Autores principales: Lai, John, An, Jiyuan, Seim, Inge, Walpole, Carina, Hoffman, Andrea, Moya, Leire, Srinivasan, Srilakshmi, Perry-Keene, Joanna L., Wang, Chenwei, Lehman, Melanie L., Nelson, Colleen C., Clements, Judith A., Batra, Jyotsna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667522/
https://www.ncbi.nlm.nih.gov/pubmed/26626734
http://dx.doi.org/10.1186/s12864-015-2235-4