Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2

T-cell development is accompanied by epigenetic changes that ensure the silencing of stem cell-related genes and the activation of lymphocyte-specific programmes. How transcription factors influence these changes remains unclear. We show that the Ikaros transcription factor forms a complex with Poly...

Descripción completa

Detalles Bibliográficos
Autores principales: Oravecz, Attila, Apostolov, Apostol, Polak, Katarzyna, Jost, Bernard, Le Gras, Stéphanie, Chan, Susan, Kastner, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667618/
https://www.ncbi.nlm.nih.gov/pubmed/26549758
http://dx.doi.org/10.1038/ncomms9823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667618/
https://www.ncbi.nlm.nih.gov/pubmed/26549758
http://dx.doi.org/10.1038/ncomms9823

Ejemplares similares