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Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2

T-cell development is accompanied by epigenetic changes that ensure the silencing of stem cell-related genes and the activation of lymphocyte-specific programmes. How transcription factors influence these changes remains unclear. We show that the Ikaros transcription factor forms a complex with Poly...

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Detalles Bibliográficos
Autores principales:	Oravecz, Attila, Apostolov, Apostol, Polak, Katarzyna, Jost, Bernard, Le Gras, Stéphanie, Chan, Susan, Kastner, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667618/ https://www.ncbi.nlm.nih.gov/pubmed/26549758 http://dx.doi.org/10.1038/ncomms9823

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