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The therapeutic effects of SET/I2PP2A inhibitors on canine melanoma

Canine melanoma is one of the most important diseases in small animal medicine. Protein phosphatase 2A (PP2A), a well conserved serine/threonine phosphatase, plays a critical role as a tumor suppressor. SET/I2PP2A is an endogenous inhibitor for PP2A, which directly binds to PP2A and suppresses its p...

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Detalles Bibliográficos
Autores principales: ENJOJI, Shuhei, YABE, Ryotaro, FUJIWARA, Nobuyuki, TSUJI, Shunya, VITEK, Michael P., MIZUNO, Takuya, NAKAGAWA, Takayuki, USUI, Tatsuya, OHAMA, Takashi, SATO, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Veterinary Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667663/
https://www.ncbi.nlm.nih.gov/pubmed/26062569
http://dx.doi.org/10.1292/jvms.15-0193