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Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling

Cancer stem cells (CSCs) are involved in tumorigenesis, tumour recurrence and therapy resistance and Wnt signalling is essential for the development of the biological traits of CSCs. In non-small cell lung carcinoma (NSCLC), unlike in colon cancer, mutations in β-catenin and APC genes are uncommon;...

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Detalles Bibliográficos
Autores principales: Fang, Lishan, Cai, Junchao, Chen, Baixue, Wu, Shanshan, Li, Rong, Xu, Xiaonan, Yang, Yi, Guan, Hongyu, Zhu, Xun, Zhang, Le, Yuan, Jie, Wu, Jueheng, Li, Mengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667703/
https://www.ncbi.nlm.nih.gov/pubmed/26468775
http://dx.doi.org/10.1038/ncomms9640