Embracing failure: What the Phase III progesterone studies can teach about TBI clinical trials

Background: Despite positive preclinical studies and two positive Phase II clinical trials, two large Phase III clinical trials of progesterone treatment of acute traumatic brain injury (TBI) recently ended with negative results, so a 100% failure rate continues to plague the field of TBI trials. Me...

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Detalles Bibliográficos
Autor principal: Stein, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667711/
https://www.ncbi.nlm.nih.gov/pubmed/26274493
http://dx.doi.org/10.3109/02699052.2015.1065344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667711/
https://www.ncbi.nlm.nih.gov/pubmed/26274493
http://dx.doi.org/10.3109/02699052.2015.1065344

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