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Embracing failure: What the Phase III progesterone studies can teach about TBI clinical trials
Background: Despite positive preclinical studies and two positive Phase II clinical trials, two large Phase III clinical trials of progesterone treatment of acute traumatic brain injury (TBI) recently ended with negative results, so a 100% failure rate continues to plague the field of TBI trials. Me...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Informa Healthcare
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667711/ https://www.ncbi.nlm.nih.gov/pubmed/26274493 http://dx.doi.org/10.3109/02699052.2015.1065344 |