Cargando…

Super-resolution imaging of nuclear import of adeno-associated virus in live cells

Adeno-associated virus (AAV) has been developed as a promising human gene therapy vector. Particularly, recombinant AAV vector (rAAV) achieves its transduction of host cells by crossing at least three physiological barriers including plasma membrane, endosomal membrane, and nuclear envelope (NE). So...

Descripción completa

Detalles Bibliográficos
Autores principales: Kelich, Joseph M, Ma, Jiong, Dong, Biao, Wang, Qizhao, Chin, Mario, Magura, Connor M, Xiao, Weidong, Yang, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667716/
https://www.ncbi.nlm.nih.gov/pubmed/26665132
http://dx.doi.org/10.1038/mtm.2015.47