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Antibody Binding Selectivity: Alternative Sets of Antigen Residues Entail High-Affinity Recognition
Understanding the relationship between protein sequence and molecular recognition selectivity remains a major challenge. The antibody fragment scFv1F4 recognizes with sub nM affinity a decapeptide (sequence (6)TAMFQDPQER(15)) derived from the N-terminal end of human papilloma virus E6 oncoprotein. U...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4667898/ https://www.ncbi.nlm.nih.gov/pubmed/26629896 http://dx.doi.org/10.1371/journal.pone.0143374 |